Description of the drug, pharmaceutical forms and characteristics
Miramistin is a local antiseptic containing benzylmethyl ammonium chloride monohydrate as the main active ingredient. The mass fraction of the substance is 100 mg per 100 ml of the finished solution. Of the auxiliary components, only distilled water is isolated.
On the pharmaceutical market, the drug is presented in the form of a solution intended for topical use. The liquid is normally colorless; when shaken, foam formation is permissible.
The solution is packaged in a polyethylene bottle and cardboard box. The volume of the bottle can range from 50 to 200 ml. For ease of use, the kit includes a spray bottle or spray nozzle. There are no tablets or suppositories produced.
Miramistin during pregnancy is used to treat colds and sore throats
The bactericidal effect of the drug is manifested against gram-positive and gram-negative representatives of aerobic and anaerobic bacterial agents, including hospital strains that exhibit resistance to antibacterial agents.
The antifungal mechanism of action develops against aspergillus, yeast flora and yeast-like fungi, dermatophytes, and other fungi with pathogenic activity. The antiviral effect develops when exposed to complex viruses, herpes viruses and immunodeficiency viruses.
Prevention of the infection process is achieved by accelerating the process of restoration of wound defects, stimulating protective reactions, as well as activating the absorption and digestive functions of phagocytes. Effective relief of wound and perifocal inflammatory processes is achieved due to pronounced hyperosmolar activity.
Miramistin for intimate hygiene
Intimate hygiene is an excellent prevention of most diseases. That is why it must be carried out using appropriate means. The ideal option in this case is Miramistin.
What is Miramistin?
Miramistin is an antibacterial drug that has a wide spectrum of effects. This medicine is used to treat various infectious pathologies. The use of the drug is recommended not only for therapy, but also for the prevention of various diseases. The drug is used for diseases that have different etiologies:
- Bacterial;
- Viral;
- Fungal.
The preparation of the medicine is carried out in the form of a solution, ointment and spray, which provides the opportunity to choose the most suitable form for a woman.
Use of Miramistin in gynecology
Miramistin belongs to the category of safe drugs and is therefore widely used in gynecology to treat a variety of diseases. The use of the drug after childbirth is most often recommended to eliminate the possibility of wound suppuration. It is recommended to use the drug to eliminate infectious processes in the vagina and external genitalia.
With the help of Miramistin, a variety of gynecological diseases that are bacterial in nature are treated. The drug is often used for inflammation of the vagina and appendages. The use of the medication is recommended for women diagnosed with endometritis.
If a woman has inflammatory processes in the vagina or appendages. The use of the medication is recommended for the treatment of various venereal pathologies:
- Gonorrhea;
- Trichomoniasis;
- Chlamydia.
In some cases, Miramistin is prescribed to increase the sensitivity of pathogenic microorganisms to other medications.
Is it possible to use Miramistin during pregnancy for intimate hygiene?
Miramistin is not absorbed into the body through mucous membranes. That is why doctors allow the use of medicine for intimate hygiene during pregnancy. According to the results of various studies, it can be concluded that the drug does not harm the fetus. That is why its use is permitted at various stages of the disease.
Despite the fact that an overdose of the drug does not lead to various disorders in the development of the fetus, it should not be abused. This is explained by the fact that the likelihood of developing allergic reactions in the fetus increases. At the moment, there have been no specific cases of negative effects of Miramistin on the fetus.
Treatment of thrush in women with Miramistin
Therapy of candidiasis with Miramistin requires the correct prescription of the medication. To treat the mucous membranes of the vagina, it is necessary to use a solution of this drug. A piece of gauze is moistened in it, with which the treatment is carried out. The manipulation should be carried out only after hygiene procedures.
If a representative of the fairer sex has deep damage to the mucous membranes, then the medication must be used intravaginally.
In this case, a gauze swab is soaked in the solution and inserted into the vagina. A woman must first thoroughly wash her external genitalia.
To ensure the highest possible effectiveness of the procedure, it must be carried out in the evening. The tampon is removed from the vagina in the morning.
How to use Miramistin for intimate hygiene
For intimate hygiene, it is recommended to use Miramistin solution. It is added to a bowl of water for washing. You can also moisten a napkin in the solution and wipe the external genitalia with it. The procedure must be carried out daily. After performing hygiene procedures, a woman is recommended to refrain from urinating for several hours.
To disinfect the external genitalia, you can use a drug that is produced in the form of a spray. With the help of this product, pathogenic bacteria are effectively combated, which is explained by the presence of antiseptic properties. The spray must be sprayed onto the external genitalia after hygiene procedures.
Precautionary measures
To avoid undesirable consequences, the drug must be used in compliance with certain rules. In case of individual intolerance to the components of the medicine, its use for intimate hygiene and treatment of various diseases is strictly prohibited. Otherwise, complications may occur that manifest themselves in the form of allergic reactions.
If after carrying out hygienic procedures a burning sensation is observed in the perineal area, then it is necessary to urgently rinse with clean water. In the future, the use of the drug for intimate hygiene is prohibited.
Indications for use in the first trimester of pregnancy
Miramistin in the throat during pregnancy is prescribed in the following cases:
- inflammatory diseases in the oral cavity (stomatitis, gingivitis, periodontitis);
- sinusitis;
- inflammation of the larynx;
- pharyngitis;
- otitis;
- chronic form of tonsillitis.
A pronounced therapeutic effect is observed when Miramistin is used during pregnancy to treat angina in the initial stages, which has a different origin.
Rules for using Miramistin during pregnancy
There are separate rules for using the drug, taking into account the specifics of the disease.
Into the throat
To eliminate diseases, the product can be used as a rinse or inhalation. When rinsing, the patient needs to take 10 ml of the drug. The average duration of the procedure is 2-3 minutes.
The product must be used up to 4-5 times daily. Inhalations are rarely carried out, which is explained by the high likelihood of developing allergic reactions. Add 5 ml of product to the nebulizer container.
Into the nose
Instillation into the nose is possible only after consultation with a specialist. In this case, the drug can not only have an antiseptic effect for a runny nose, but also prevent the spread of infection to other parts. Due to its irritating effect on the mucous membrane, the use of this product is limited.
For otitis media
For the treatment of otitis, Miramistin can be used for catarrhal and purulent forms.
The product is instilled into the ear canal, heated to a comfortable temperature, 1 ml of solution. Instillations are made three times per day for 7-10 days.
Inhalations
Inhalations are rarely carried out, as there is a high probability of developing an allergic reaction. Add 5 ml of product to the nebulizer container.
Throat treatment with Miramistin: rinse and spray
Miramistin can be used as part of complex therapy for ENT diseases.
For inflammatory diseases of the throat (sore throat, pharyngitis, tonsillitis), gargling or irrigating the throat with a spray is indicated.
This achieves an anti-inflammatory, regenerating, antiseptic effect.
Gargling with Miramistin solution is done 4-5 times a day. For one procedure you will need 10-15 ml of the drug. The medicine should not be swallowed; after rinsing, you must refrain from eating and drinking for 30 minutes.
If there is a need for more frequent gargling, then Miramistin solution should be alternated with other non-medicinal agents.
Pregnant women are allowed to use infusions of chamomile, sage, calendula, a solution of soda or sea salt for this purpose.
To irrigate the throat, a special spray nozzle is installed on the bottle, which comes complete with the solution. To treat the mucous membrane of the throat, 2-4 presses on the sprayer are enough. During irrigation, you must hold your breath. The procedure can be repeated up to 6 times a day.
How to gargle with Miramistin during pregnancy
Miramistin in the throat during pregnancy is also used to treat sore throat, as well as pharyngitis or tonsillitis. The use of a 0.01% solution is indicated. In order to achieve the maximum therapeutic effect, first rinse with warm, clean water.
Next, you need to take 15-20 ml of solution into your mouth, throw back your head and gargle for 1 minute. The remaining solution is spat out and local medications are not used, and food is not allowed for 30 minutes.
The use of Miramistin in the maternity hospital
If a pregnant woman spends the last days before giving birth in a hospital, she undergoes sanitization of the birth canal.
This procedure allows you to cleanse them of pathogenic microflora and prevent infection of the child during childbirth.
Douching during pregnancy is allowed only in a hospital, since improper implementation of the procedure can lead to unpleasant consequences for the woman and child.
Sanitation with Miramistin is carried out by vaginal irrigation (douching) for 5-7 days.
If a child is born via cesarean section, the vagina is treated with the drug before the operation, and the uterine cavity and incision are treated with the drug during the operation. To prevent infectious complications after childbirth, a tampon soaked in Miramistin solution is inserted into the vagina. The procedure lasts 2 hours and is repeated daily for 5-7 days.
How to replace the drug during pregnancy
There are several medicines on the pharmaceutical market that can replace Miramistin.
Chlorhexidine
A drug containing chlorhexidine bigluconate has antiseptic properties. On the pharmaceutical market, the drug is presented in two concentrations, containing the main active ingredient 0.5 mg and 0.2 g. Dosage forms include bottles with and without a sprayer, as well as suppositories, creams and gels.
The main mechanism of action is based on a local antiseptic effect, which manifests itself primarily against bacterial agents. Once on the surface of the bacterial cell wall, it changes its properties. As a result, the cytoplasmic membrane is destroyed and the bacterium dies.
The greatest activity is manifested against Trichomonas, chlamydia, gardnerella, gonococci and ureaplasma. At the same time, resistance to viral and fungal particles is noted.
When applied externally, Chlorhexidine is not absorbed, therefore, it does not penetrate into the systemic circulation. Before use, it is necessary to exclude contraindications, including individual intolerance to the substance or the simultaneous use of another antiseptic.
It should be noted that the drug can lead to the development of side effects such as dry mucous membranes, itching , and polymorphic rashes. Rarely, patients are concerned about impaired taste sensitivity, the appearance of tartar, and or changes in the color of tooth enamel.
For the treatment of sore throat, pharyngitis or tonsillitis, the use of Chlorhexidine in any concentration is allowed. You should first rinse your mouth with warm water. For one-time use, 10-15 ml of solution is sufficient. The average duration of application should not be less than 30 seconds.
If, when rinsing, a burning sensation and itching occurs in the oral cavity, you need to stop using the product and seek help from a doctor. The patient may be using a higher concentration of the drug. In addition, it is forbidden to swallow Chlorhexidine. If a woman swallows the product, she must take one or two tablets of activated carbon.
Furacilin
Miramistin during pregnancy (several proven drugs can be used in the throat instead) can be replaced with the well-known furatsilin. The drug, produced in the form of a solution, is made on the basis of nitrofural and auxiliary components.
Solutions may contain an aqueous base consisting of distilled water or 70% ethyl alcohol. Combination preparations are produced, which include Furacilin.
Nitrofural, on the basis of which the drug is made, is a yellow or greenish powder that tastes bitter and has a fine-crystalline structure.
Its mechanism of action is based on interaction with bacterial cell wall proteins, resulting in the formation of amino derivatives that can change the confirmation of bacterial cells.
Disruption of metabolic processes in it leads to inevitable death, and an increase in the absorptive capacity of the macrophage system leads to increased phagocytosis.
The product is effective against gram-positive and gram-negative bacteria, as well as viral particles and protozoa.
The greatest sensitivity is noted to streptococci, staphylococci and Escherichia coli. Resistance to Furacilin develops slowly, but it becomes pronounced. It can be effective when pathogenic microorganisms are resistant to other antimicrobial agents.
Furacilin is approved for use at any gestational age. This is due to the fact that when applied externally, the drug is not absorbed into the bloodstream. When gargling, do not swallow the product.
Furacilin (namely a solution of the drug) is used to gargle for inflammatory diseases of the throat
Indications for use in diseases of the throat include inflammatory diseases, including infectious diseases in the oral cavity and larynx, sinusitis and frontal sinusitis. To do this, the patient needs to prepare a solution of two tablets and 200 ml of warm distilled water.
The tablet must first be crushed in order to dissolve faster. To enhance the therapeutic effect, add 3% hydrogen peroxide in a volume of 2 tsp to the resulting solution. The average rinsing time should be from 3 to 5 minutes. The course of treatment is 7-10 days.
Octenisept
Miramistin can be replaced with Octenisept. It refers to antiseptic solutions intended for external use. The main active ingredients contain octenidine and phenoxyethanol. The pharmaceutical market offers bottles ranging from 50 ml to 1 liter with a spray bottle.
Its mechanism of action is based on the destruction of gram-positive and gram-negative bacterial flora, viral particles with lipophilic activity, including herpes simplex and hepatitis viruses, and yeast-like fungi.
For diseases localized in the mouth and throat, it can be used from the first weeks of pregnancy. This is due to the absence of a toxic effect that negatively affects the fetus. To distribute the product evenly throughout the oral cavity, it is recommended to use it in the form of a spray. Octenisept can be used in pure form, as well as in a dilution of 1:1 or 1:5.
A single dose is 20 ml, and the rinsing duration is 1-2 minutes. Re-irrigation is possible after 20 seconds. To prevent side effects, it is not recommended to combine Octenisept with other antiseptics.
Chlorophyllipt
A topical solution based on eucalyptus may have an alcohol or oil base. The drug has bactericidal and bacteriostatic effects. The etiotropic effect is manifested against various bacteria, including antibiotic-resistant and antibiotic-dependent strains of staphylococci.
It eliminates genes that carry resistance to antibacterial agents, increasing the concentration of oxygen in tissues. After use, a pronounced detoxification effect is observed. When used simultaneously with antimicrobial agents, the therapeutic effect is enhanced.
Chlorophyllipt is approved for use from early stages of pregnancy , since embryotoxic, teratogenic, mutagenic and carcinogenic effects do not develop during treatment. The remedy is indicated for laryngitis, pharyngitis and tonsillitis, as well as aphthous or ulcerative stomatitis.
The mouth or throat can be treated by spraying at intervals of up to 3-4 times daily. The duration of treatment is 4-5 days. Before using Chlorophyllipt for pregnant women, it must first be diluted in warm water at the rate of 5 ml per 0.5 liter of warm water.
Miramistin venereology: when it can help, how to use
Sexually transmitted diseases are a group of infectious diseases that are transmitted primarily through sexual contact.
The causative agents can be various groups of microorganisms: protozoa, bacteria, viruses.
To combat them, antiseptics are used, which are applied topically.
Miramistin is one of these drugs.
Since the drug is active against STIs, it is used in venereological practice externally at the site of the lesion.
Properties of Miramistin
The main active ingredient is benzyldimethyl.
The mechanism of action of the substance is based on the destruction of the cell wall of pathogens.
But the epithelial cells of the urogenital tract are not exposed to the negative effects of Miramistin.
This property allows it to be successfully used in venereology.
The antiseptic is used not only for the treatment of urogenital infectious diseases, but also in other areas of medicine.
The drug has an antimicrobial effect against protozoa, bacterial microflora, fungi, and viruses.
Miramistin is able to cope with HIV and the herpes virus.
The drug is effective even against strains of bacteria that are resistant to antibiotics.
Because of this property, it is used for preventive and sometimes medicinal purposes.
Among the advantages of the drug:
- It should be noted that there is no irritating effect. The product does not cause chemical burns, discomfort in the form of tingling or burning sensation. Patients easily tolerate treatment. If there are ulcerations or erosions on the mucous membrane, then the use of Miramistin in no way affects the ability of tissues to regenerate.
- Lack of ability to penetrate deeply into tissues and into the systemic circulation, even when used in large quantities. As a result, there are no side effects, which ensures the safety of the drug.
Studies have found that the drug is highly effective if used in conjunction with antibacterial agents.
In combination with antibiotics, Miramistin has a stronger effect.
Features of the drug Miramistin
Before using Miramistin, you must carefully read the instructions.
Since the drug has some features:
- When using the product, a slight burning sensation may be noted, which is acceptable. As a rule, the discomfort quickly goes away on its own.
- Miramistin is a drug whose effect is manifested only externally, so it is not prohibited to use during pregnancy.
- If you have individual intolerance, which is manifested by swelling, hyperemia, itching, burning, and the appearance of spots, you should inform your doctor. In this case, it is better to replace the drug with another antiseptic.
Does Miramistin help against infections?
Miramistin is most effective against bacterial cells, against fungal infections and Trichomonas.
Treponema pallidum, gonococcal infection, streptococci, and staphylococci are sensitive to it.
Miramistin exhibits selective activity against viruses.
For example, the instructions for use say that the drug inhibits the herpes and HIV viruses.
The drug has an anti-inflammatory and immunostimulating effect.
It can dry out inflamed areas without interfering with the formation of epithelial cells.
Venereologists confirm that Miramistin can be used as emergency preventive measures.
- The drug is maximally effective against gonococci, trichomonas, Treponema pallidum and Candida fungi.
- If previously Miramistin was used to treat myco- and ureaplasma infections, at the moment it is impossible to talk about one hundred percent prevention of infection with these pathogens.
- The drug does not show particular activity against chlamydia, since they can form D-forms, allowing them to evade the effects of Miramistin.
- The product does not provide protection against hepatitis B and C, since the pathogen enters the body through microcracks, and the antiseptic only works from the outside.
- The causative agent of genital herpes and papillomavirus can be transmitted not only during sexual contact, but also in other ways, so Miramistin cannot provide one hundred percent safety.
How to use Miramistin after sex
The antiseptic is widely used in venereology after unprotected intimate intercourse.
You can learn how to use Miramistin correctly to prevent infection by reading the instructions.
Miramistin is used to treat the urethra in the stronger sex, and the urethra and vagina in women.
If there was an oral type of sexual contact, it will be necessary to treat the oral cavity, and the rectum in the case of anal contact.
This measure is necessary because sexually transmitted infections can provoke the development of pharyngitis or proctitis.
The treatment does not prevent infection, but is often effective and helps prevent disease if done within two hours of sexual intercourse.
Method of using Miramistin by men after sex:
- To start using the antiseptic, you need to remove the cap from the bottle.
- Attach the nozzle for insertion into the urethra and inject the product in an amount of 2-3 ml.
- Keep the antiseptic in the urethra for as long as possible, but not less than 3 minutes.
- Additionally, treat the pubic area, genitals and inner thighs.
Women should use Miramistin after unprotected sex in the same way:
- Since the female urethra is very short, no more than 2 ml of antiseptic is injected into it.
- A special nozzle is used to treat the vagina. Having put it on, you need to insert about 10 ml of Miramistin into the vagina and hold it there for some time.
- Hips can be treated using a spray nozzle.
Preventive measures should be taken if no more than 2 hours have passed after sex.
It’s even better if you do the treatment right away.
It makes sense to use Miramistin after unprotected sex even if a little more time has passed.
After 5 hours, the antiseptic will not be able to eliminate the possibility of infection.
In any case, you need to visit a doctor.
A specialist has more effective preventive techniques in his arsenal.
This is, for example, instillation of deeper parts of the urethra and the prescription of agents with antimicrobial activity.
How to use Miramistin during oral sex
The use of the drug is also effective in case of oral-genital contact.
Many infections can be transmitted this way.
These include gonorrhea, genital herpes, and syphilis.
If there has been unconventional sexual intercourse, then using Miramistin after oral sex can completely eliminate the possibility of infection.
To do this, rinse your mouth well with an antiseptic.
In the oral cavity, infections are more difficult to manifest themselves than in the urogenital tract.
Therefore, the use of an antiseptic will highly likely reduce the risk of infection by pathogenic bacterial microflora.
Miramistin is more difficult to cope with a viral infection.
How to use Miramistin if anal sex has taken place
After anal sex, doctors recommend using Miramistin to treat the rectum to destroy invading pathogens.
This preventative measure will reduce the likelihood of developing proctitis.
Infectious lesions of the rectum are a rather delicate problem.
The disease may be asymptomatic, and in some cases may be accompanied by pain in the rectum, the presence of pathological discharge, false urges or constipation.
The use of Miramistin will help prevent such symptoms from developing.
Is Miramistin effective if used before sex?
The instructions included with the drug do not indicate whether it is necessary to use an antiseptic before having unprotected sex.
This measure is ineffective.
Miramistin does not make sense to use for sex.
The antiseptic was created to protect against possible infection if a pathogen suddenly gets on the mucous membranes.
If there is information that a sexual partner is infected with a contagious disease, you should not have sexual intercourse.
It should be understood that Miramistin cannot 100% exclude infection, i.e. a person will still get sick.
Why contact the patient?
It must first be cured so that it cannot spread pathogens.
If you urgently need to have sexual intercourse with a patient, then, as a last resort, you can use a condom.
It can serve as protection against many infections.
If you don’t have a condom, you can use Miramistin, but even in this case the product does not protect against infection.
Can Miramistin be used for STDs?
Miramistin should not be used in the presence of sexually transmitted infections.
The drug is prescribed for emergency prevention of STIs.
The drug cannot penetrate deep into the tissue to kill all pathogenic microflora.
For this reason, the product is not used for sexually transmitted infections.
For nonspecific infection, Miramistin can be used.
For prevention, it is injected into the urethra one to two times a day for ten days.
When infected with a sexually transmitted disease, the drug is prescribed in complex therapy.
To do this, the patient takes antibiotics orally or by injection.
An antiseptic is used for local therapy as an adjunct, without excluding the use of antibacterial drugs, which allows you to quickly remove symptoms.
Moreover, the use of Miramistin does not affect the change in dosage in the direction of reducing other drugs.
If you read reviews of people who have used Miramistin, there is information about the high effectiveness of the drug as a prophylactic agent, and therefore it is actively used in venereology.
An antiseptic reduces the risk of developing the disease several times.
But, as a rule, this is not enough.
It is necessary to go to a specialist so that he can prescribe more effective preventive measures.
Also, after prophylaxis with Miramistin, the patient will need to undergo tests in two weeks to understand whether infection has occurred.
You should not assume that if there are no symptoms, then there is no disease.
Most infections are hidden or symptoms appear very late.
In this case, the patient can serve as a source of infection for the people around him.
There is a high risk of developing negative consequences, which may include the inability to conceive a child.
If pregnancy occurs, then, as a rule, it may end in miscarriage.
Therefore, it is imperative to go to the doctor to undergo an examination in order to exclude hidden pathology.
Currently, there are many types of tests, so getting diagnosed will not be difficult.
If the test is positive, treatment should be started immediately.
Release forms of the drug Miramistin
The manufacturer of the drug is the company Infamed.
Miramistin is produced in bottles of various sizes.
Their capacity ranges from 50 to 0.5 liters.
Depending on the quantity, the product has a specific purpose.
Small volume bottles are equipped with two attachments: gynecological and urological.
As a rule, they are recommended to be used for preventive purposes.
For this purpose:
- no spray nozzle required
- small volume is enough for one-time processing
There is no need to store the drug in reserve, because the drug is used once only if there has been sexual intercourse without using a condom.
Larger volume bottles are applicable for other cases: used in burn and surgical departments.
The package includes a spray nozzle designed to:
- for treating large affected areas of the skin
- for treating the throat and oral cavity - in dental practice and in cases of damage to the pharynx and tonsils
As a rule, this volume is enough to carry out the procedure several times a day for one to two weeks.
The largest containers with a volume of 0.5 liters are not applicable at home.
They are used in inpatient hospital settings.
Medical clinics purchase them in large quantities because they are cost-effective.
One package contains 12 bottles of 0.5 liters each.
For advice on the use of Miramistin as a preventive measure for STDs, please contact the author of this article, a venereologist in Moscow with many years of experience.
Source: https://www.venerologia.ru/miramistin-v-venerologii
Comparative characteristics of Miramistin and its analogues
Miramistin | Chlorhexidine | Furacilin | |
Main active ingredient | Benzylmethyl ammonium chloride monohydrate | Chlorhexidine bigluconate | Nitrofural |
average cost | 200-250 rub. | 40-50 rub. | 30-50 rub. |
Therapeutic effect | Antiseptic | Antiseptic, except for complex viruses | Antiseptic, allows you to destroy even resistant forms of microorganisms |
Composition and release form
Miramistin contains benzyldimethyl ammonium chloride monohydrate as an active substance. Additional elements: purified water.
Available in the form of a solution for topical use. It is colorless, odorless and absolutely transparent. When shaken, foam forms.
It goes on sale in bottles of various dosages (from 50 ml to 500 ml). Eye drops are used in hospital settings.