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One of the most common remedies is Ibuprofen for headaches. Most of the population suffers from headaches. Mostly people resort to painkillers.
General information about the drug
Ibuprofen is considered a non-steroidal anti-inflammatory drug and has antipyretic and analgesic effects. After taking the tablet, a minute later it dissolves in the stomach. After 5 - absorption into the intestines and stomach walls occurs. And after 10 minutes, the anti-inflammatory effect begins, and the pain syndrome subsides.
Ibuprofen can be classified as an effective and safe pain reliever. It is also well tolerated by the body. It has many analogues and dosage forms, which are preferred by many people around the world. Once in the body, the tablet suppresses the activity of the enzyme cyclooxygenase, that is, it blocks the formation of inflammation. The pain weakens and completely disappears. This enzyme is considered the main one in the metabolic process. Ibuprofen tablets do not contain preservatives. They contain sucrose.
Among the many ibuprofen analogues, the main ones stand out:
- Classic, it contains 200 ml of Ibuprofen. For mild to moderate pain, this drug is recommended.
- Express, it acts much faster than the classic one, it is used for severe headaches.
- Forte contains a double dose of Ibuprofen, it is recommended in the treatment of migraines.
How to take the medicine?
Before you start taking any pills, you need to carefully read the instructions.
This medicine should be taken after meals. Take the tablet with a small amount of water. Take 1 tablet 3 times a day.
Cases in which you should not take Ibuprofen:
- For diseases of the gastrointestinal tract, heart failure and kidney diseases, as well as for children under 6 years of age.
- Damaged blister of new packaging.
- If you have allergic reactions to some components of Ibuprofen;
- Late term pregnancy.
- Do not exceed the permissible doses; discuss taking pills for more than 3 days with your doctor;
- You need to know that combining alcohol and Ibuprofen can lead to liver dysfunction.
- Effect on the nervous system - dizziness, impaired vision and sleep.
- On the digestive system - the presence of nausea, vomiting, diarrhea, possible damage to the gastrointestinal tract, and with long-term use, liver damage may occur.
- Effect on the circulatory system - with prolonged use, anemia is possible.
- With long-term use, renal function may be impaired.
- Allergic reactions are possible.
A little bit of history.
The drug was released in 1962. Its first name is Brufen. It was synthesized by John Nicholson and Stuart Adams. It was used in the treatment of rheumatoid arthritis. And in 1974, in the United States of America, it was used as an antipyretic and pain reliever under the name Motrin. During these years it was sold only by prescription. And already in 1983 in the UK it began to be sold without a prescription. In 1985, the company that produced this drug received the Queen's Award for Scientific and Technical Achievement. Ibuprofen is now used in more than 120 countries around the world.
Interaction with other drugs
Taking Ibuprofen is not recommended together with acetylsalicylic acid and other drugs from this group, as it reduces the antiplatelet and anti-inflammatory effects of aspirin. If you take Ibuprofen and thrombolytic medications, there is a risk of bleeding. And taking serotonin with Ibuprofen can affect the development of bleeding in the gastrointestinal tract.
Advantage of Nurofen
Placebo-controlled studies have shown that ibuprofen is effective in combating various types of headaches. After using the first tablet you can already feel the result. Another advantage is the rapid elimination of the drug from the body, while it does not form toxic metabolites. The analgesic effect lasts more than 6 hours. In terms of the number of side effects, Ibuprofen also showed itself to be better than other drugs.
Combinations based on Ibuprofen
Ibuprofen and Paracetamol - Ibuklin, Brustan, Next - are a powerful analgesic and antipyretic. They should be taken only when headaches are not relieved by simple Ibuprofen. Brustan and Ibuklin take 1 tablet before meals, but you can also take it after, but not earlier than 2 hours later and no more than 4 times a day. Next is taken after meals, 1 tablet 3 times a day.
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Ibuprofen, Pitophenone and Fenpiverinium bromide - Novigan. It is an antispasmodic and analgesic. Used for headaches caused by vascular spasms. It should be taken one hour before meals or 3 hours after. Take 1 tablet no more than 3 per day.
Name of drugs with the active ingredient ibuprofen:
- Buran, Ibufen, Mig, Nurofen, Nurofen Ultracap, Nurofen Express, Nurofen Faspik.
- Ibuklin relieves pain in children.
The drug Ibuclina has been released, intended for children from birth. It not only relieves headaches, but is also effective in treating otitis media and tonsillitis.
Ibuprofen is an effective and safe analgesic not only in pain relief, but also in the course treatment of chronic pain. It treats headaches of various origins: colds and flu, hangover syndrome, psychogenic cephalalgia, abdominal and combined headaches, migraine and cervicogenic. It has the added benefit of being available in several dosage forms.
Description of the drug Ibuprofen for influenza and ARVI
Ibuprofen is a drug for relieving pain in various diseases, including relieving aches, headaches and a rapid drop in temperature during ARVI or influenza. This drug is available in various forms, in particular, it can be purchased in the form of tablets (the most common form of the drug), as well as suspensions for children.
Cost from 30 rub.
Ibuprofen is available in pharmacies without a prescription, but it is important for patients to remember that the drug is potent, and its use without prior examination by a doctor and appropriate prescription can have negative consequences for human health, especially if the patient suffers from any chronic diseases.
In addition to the main name “ibuprofen”, the drug can be found in pharmacies under the names “nurofen”, “ibuprom”, “ibufen”, “brustan”, as well as some others. Before purchasing and taking such drugs, it is important to carefully study their composition and the dosage of the active substance in each type of tablet to ensure effective treatment.
The many faces of Ibuprofen
Today, Ibuprofen is present in pharmacies under dozens of different names: Advil, Ibufen, Brufen, Bufen, Dolgit, Ib-Tab, Ibuxin, Rimafen, Salvarina, Unafen and so on.
These products differ in dosage, design, additives, but the active ingredient in them is the same - it is (RS)-2-(4-isobutylphenyl) - propionic acid, that is, ibuprofen.
One of the most popular types of ibuprofen is the heavily advertised drug Nurofen. In fact, this is a whole line of drugs based on ibuprofen. Nurofen was first produced by the British-Dutch company Reckitt Benckiser in 1983. This is not a pharmaceutical company. Its specialization is very diverse - household goods, cleaning products and disinfection, household chemicals, personal hygiene items, skin care products, condoms (the famous Durex), medicines.
Currently, Nurofen is one of the most popular medications sold without a prescription. This is facilitated by both the high effectiveness of ibuprofen and aggressive advertising.
In total, pharmacies offer 11 options for Nurofen. It may be in the form of regular hard or soft gel tablets. For external use, a gel is used that must be applied to the skin. Nurofens differ not only in the concentration of the active substance, but also in the rate of its absorption. For example, ibuprofen from Nurofen, which is marketed as a headache remedy, is absorbed almost twice as quickly as from Nurofen, which is marketed to relieve painful menstruation. In the first case, the maximum concentration in the blood after administration is reached after 40 minutes, and in the second - after 80.
Some types of Nurofen contain additional substances. For example, Nurofen Cold & Flu (for colds) contains pseudoephedrine, which helps with nasal congestion but can cause insomnia and nervousness. And Nurofen Plus also contains codeine phosphate, which is an opioid analgesic.
It is interesting to note that the medical community is skeptical about the advertising of Nurofens, and the greatest objections are raised by claims that different Nurofens affect different types of pain. There have even been complaints about this that the advertising is misleading to patients. As a result, the advertising was slightly changed.
Pharmacological action and group
This drug belongs to the category of non-steroidal anti-inflammatory drugs. This remedy is most effective for inflammatory processes. Ibuprofen has a pronounced antipyretic and anti-inflammatory effect, which is ensured by a non-selective blockade of cyclooxygenase. The drug is well absorbed by the walls of the stomach; if this drug is taken after meals, its effect is slightly reduced. The remains of the drug are eliminated through the kidneys, which is why it is not recommended for people with impaired kidney function.
What causes an overdose
The state of intoxication depends on the amount of medication taken and on how much time has passed since taking it.
Overdose symptoms:
- Stomach pain, nausea, vomiting, diarrhea.
- Problems with vision, blurry images, double objects.
- Enlarged and/or painful liver, yellow sclera and skin.
- Signs of internal bleeding, blood on the tongue.
- Reduced heart rate, less than 50 beats per minute.
- Blueness of the skin.
- Difficulty in kidney function.
Ibuprofen intoxication in children manifests itself in the form of weakness, drowsiness, and uncontrolled decrease in body temperature.
If the described signs are observed, it is necessary to urgently seek emergency help to exclude the negative consequences of a drug overdose. If assistance is not started in a timely manner, pathological disturbances in the functioning of the respiratory and cardiac systems will occur, causing the death of the victim from intoxication.
Indications and contraindications for the use of Ibuprofen - instructions for use
Ibuprofen may be indicated for patients who have been diagnosed with the following diseases:
- pain syndromes caused by injuries of joints and soft tissues;
- dystrophic pathologies of the joints and spine, accompanied by severe pain syndromes (including osteoarthritis and rheumatoid arthritis);
- infectious diseases of the respiratory tract, including sore throat and pharyngitis;
- articular syndrome;
- neuralgia of various types;
- psoriatic arthritis.
This drug is also prescribed for severe headache or toothache, or fever accompanied by various infectious diseases.
Ibuprofen also has a number of contraindications for use. So it is not prescribed to patients who:
- have hypersensitivity to various components of the drug;
- suffer from gastric or intestinal ulcers, especially in the acute phase;
- have acute or chronic liver or kidney diseases;
- suffer from hematopoietic diseases;
- have disturbances in the functioning of the optic nerve.
Patients who suspect such diseases, but are not sure of the accuracy of the diagnosis, are recommended to take the drug only after preliminary diagnosis and strictly on the recommendation of the attending physician. This will make it possible to eliminate various unwanted side effects.
Ibuprofen is also prescribed with caution to children and pregnant women. It is important to consider the features of the drug in this case in more detail.
Can pregnant women take it at fever?
The instructions indicate that the use of ibuprofen is contraindicated in the last trimester of pregnancy. The drug can be used to treat pregnant women in the first and second trimester, but only if the expected effect in the treatment of a particular disease for the mother exceeds the risks to the fetus. This drug is prescribed for complex infectious diseases; it is also often included in the general treatment regimen for influenza, which gives a temperature above 39 degrees. In this case, the drug is used only in the minimum effective dosage. Violation of this rule may lead to fetal development disorders, miscarriage or other adverse reactions.
Unauthorized use of ibuprofen for pregnant women at any stage is strictly contraindicated. The drug can only be used as prescribed by a doctor and strictly under his supervision.
How to take medicine for small children
Ibuprofen can be used to treat children of all ages, including newborns. For this category of patients, the drug is prescribed mainly when fever appears, accompanying various infectious diseases, including sore throat, pharyngitis, and sometimes influenza.
Cost from 80 rub.
It is important to note that ibuprofen-based drugs for children are available in special dosages; among them there are not only tablets, but also injection solutions. Regular ibuprofen tablets are not prescribed for children under 6 years of age. The most effective children's medicines for colds and flu are presented in this material.
Prescribing ibuprofen to a child, especially a newborn, requires preliminary studies to determine the body’s sensitivity to certain components of the drug. Without such studies, treatment with ibuprofen is not carried out.
Contraindications
Taking into account the ulcerogenic effect of Ibuprofen, the drug is contraindicated for various ulcerative and erosive lesions of the gastrointestinal organs (Crohn's disease, UC, duodenal and gastric ulcers). It also cannot be used for blood clotting defects, leukopenia, pathologies of the optic nerve, thrombocytopenia, heart, kidney and liver failure.
An absolute contraindication is the patient's hypersensitivity to the composition of Ibuprofen. In addition, if there is a high sensitivity to other NSAIDs, for example, aspirin, Ibuprofen is also not prescribed. During pregnancy, the product can only be used as directed by a specialist.
So is Ibuprofen an antibiotic or not?
Many people ask, “Is Ibuprofen an antibiotic?” This is an anti-inflammatory non-steroidal drug. This pharmacological group has nothing to do with antibiotics. That is why we can safely say that Ibuprofen is not an antibiotic.
Possible complications caused by the drug for colds
Ibuprofen can have various side effects on the body depending on a person’s individual sensitivity to certain of its components, as well as the presence of chronic diseases in the patient. Ibuprofen may cause:
- damage to the walls of the gastrointestinal tract, up to the formation of ulcers;
- various disorders of the central nervous system, including headaches, dizziness, sleep problems;
- allergic reactions, including skin rash, Quincke's edema; people with hypersensitivity to individual components of the product may also experience aseptic meningitis, but this is rare;
- disorders of the circulatory system, including anemia.
Long-term use of this drug may also cause kidney problems. To avoid this, you need to refrain from unauthorized extension of the course of this drug and undergo long courses of treatment with it only under the supervision of a doctor.
In addition, the drug can also cause local reactions: burning and swelling in a certain area of the skin or tingling. As a rule, such reactions disappear after finishing the course of ibuprofen treatment.
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Side effects of stomach pain pills
The best option to quickly cope with abdominal pain is painkillers - they are available in a wide range, are quite effective and are inexpensive. Most analgesics belong to the group of non-steroidal anti-inflammatory drugs. By taking such a pill for the stomach, you can at the same time reduce the activity of the inflammatory process and normalize the temperature if the latter has been elevated.
However, despite all the positive qualities, NSAIDs can cause negative reactions in the body:
- An increase in the level of hydrochloric acid with a simultaneous decrease in mucus production, which provokes nausea, discomfort, and diarrhea. With frequent and long-term use, the formation of ulcers and erosion is possible with disruption of the integrity of the mucous membrane, the wall of the stomach or intestines.
- Increased blood density, accelerated blood clotting, which causes thrombosis and problems with the cardiovascular system.
- Kidney disease due to impaired blood circulation in them. As a result, fluid retention occurs in the body, increased blood pressure, and edema.
- Dizziness.
- Increased irritability.
- Neuritis.
- An increase in the frequency of colds and infectious diseases, which occurs due to the fact that tablets for abdominal pain suppress the maturation of a certain type of leukocytes, which are responsible for the activity of the immune system.
- Taking aspirin thins the blood, which increases the chance of bleeding.
- Analgin, when combined in the stomach with certain substances, forms carcinogens and increases the risk of cancer.
- Activate the removal of moisture from tissues. For example, they cause drying of the mucous membrane of the eyes, which negatively affects visual acuity.
NSAIDs are contraindicated for people with stomach and duodenal ulcers, when carrying and breastfeeding a child, individual intolerance to the components of the drug, bleeding disorders and bronchial asthma.
Indications
Ibuprofen, like other representatives of its group, have found wide application in modern medicine. Ibuprofen tablets are prescribed for mild to moderate pain of any location, which may be associated with pathologies such as:
- osteochondrosis;
- hematomas;
- spondylosis;
- lumbago (lumbago);
- radiculitis;
- rheumatic diseases (gout, rheumatoid arthritis);
- arthritis and arthrosis;
- fever;
- inflammation of the joint capsule - bursitis;
- inflammation of muscles, ligaments of traumatic and other nature;
- neuralgia;
- pain syndrome in the postoperative period;
- headache and toothache;
- respiratory tract diseases;
- painful menstruation and inflammation of the female reproductive system;
- nephrotic syndrome.
Pedea solution is used only in pediatric practice. It is administered intravenously to premature infants to accelerate the closure of the ductus arteriosus.
Ibuprofen ointment and gel are used externally to relieve mild to moderate pain in:
- osteochondrosis;
- radiculitis;
- lumbago;
- Do not lie;
- injuries to muscles, joints, ligaments;
- hematomas.